CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05415
Pert ID:	BRD-K57432881
Compound Name:	tiapride
Targets:	DRD2\|DRD3
MoA:	dopamine receptor antagonist
SMILES:	CCN(CC)CCNC(=O)c1cc(ccc1OC)S(C)(=O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
99693	BRD-K57432881	U2OS	10 uM	6 h	0.25	1.03	0.13	0.0	0.0	0.0
123795	BRD-K57432881	A375	1.11 uM	24 h	0.0	0.0	0.0	0.19	0.68	0.01
123837	BRD-K57432881	A549	0.37 uM	24 h	0.0	0.0	0.0	-0.2	-0.67	0.02
123870	BRD-K57432881	HA1E	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123898	BRD-K57432881	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123943	BRD-K57432881	HELA	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123964	BRD-K57432881	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123999	BRD-K57432881	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124052	BRD-K57432881	MCF10A	0.04 uM	24 h	0.0	0.0	0.0	-0.24	-0.82	0.15
124122	BRD-K57432881	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124181	BRD-K57432881	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124233	BRD-K57432881	YAPC	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132252	BRD-K57432881	MCF??7.00	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132296	BRD-K57432881	PC3	0.08 uM	24 h	0.0	0.0	0.0	-0.39	-1.31	1.71

Summary