CMap Candidate Details
Structure:
| CMap ID: | C05427 |
| Pert ID: | BRD-A34462049 |
| Compound Name: | tigecycline |
| Targets: | |
| MoA: | bacterial 30S ribosomal subunit inhibitor |
| SMILES: | CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(cc(NC(=O)CNC(C)(C)C)c(O)c4C(=O)C3C(=O)[C@]2(O)C(=O)C(C(N)=O)C1=O)N(C)C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119000 | BRD-A34462049 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.04 |
| 119025 | BRD-A34462049 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119031 | BRD-A34462049 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 119053 | BRD-A34462049 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 119057 | BRD-A34462049 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.5 | -1.67 | 15.65 |
| 119084 | BRD-A34462049 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.55 |
| 119088 | BRD-A34462049 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.62 |
| 119133 | BRD-A34462049 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119146 | BRD-A34462049 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.53 |