CMap Candidate Details
Structure:
| CMap ID: | C05433 |
| Pert ID: | BRD-K30421593 |
| Compound Name: | timolol |
| Targets: | ADRB1|ADRB2 |
| MoA: | adrenergic receptor antagonist |
| SMILES: | CC(C)(C)NC[C@@H](O)COc1nsnc1N1CCOCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 117145 | BRD-K30421593 | HCC515 | 0.125 uM | 24 h | 0.25 | 1.05 | 0.16 | 0.0 | 0.0 | 0.0 |
| 117190 | BRD-K30421593 | HEPG2 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117236 | BRD-K30421593 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117274 | BRD-K30421593 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.76 | 0.05 |
| 119960 | BRD-K30421593 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120006 | BRD-K30421593 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.06 | 0.72 |
| 120035 | BRD-K30421593 | HA1E | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120199 | BRD-K30421593 | PC3 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120223 | BRD-K30421593 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128831 | BRD-K30421593 | HELA | 0.08 uM | 24 h | 0.22 | 0.9 | 0.02 | 0.0 | 0.0 | 0.0 |