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CMap Candidate Details

Structure:
CMap ID: C05486
Pert ID: BRD-K64514229
Compound Name: toltrazuril
Targets:
MoA: antiprotozoal agent
SMILES: Cc1cc(ccc1Oc1ccc(SC(F)(F)F)cc1)-n1c(=O)[nH]c(=O)n(C)c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5474 BRD-K64514229 HA1E 10 uM 6 h 0.27 1.11 0.25 0.0 0.0 0.0
5795 BRD-K64514229 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5943 BRD-K64514229 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.99
6047 BRD-K64514229 HT29 10 uM 6 h -0.15 -0.63 0.0 -0.23 -0.79 0.1
6210 BRD-K64514229 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6580 BRD-K64514229 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37180 BRD-K64514229 A375 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
37301 BRD-K64514229 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37712 BRD-K64514229 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38534 BRD-K64514229 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52181 BRD-K64514229 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91253 BRD-K64514229 HUH7 8 uM 72 h 0.0 0.0 0.0 -0.29 -0.98 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).