CMap Candidate Details
Structure:
| CMap ID: | C00055 |
| Pert ID: | BRD-K07753030 |
| Compound Name: | acecainide |
| Targets: | SCN5A |
| MoA: | polarization inhibitor |
| SMILES: | CCN(CC)CCNC(=O)c1ccc(NC(C)=O)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122587 | BRD-K07753030 | A549 | 1.11 uM | 24 h | -0.29 | -1.22 | 0.61 | -0.17 | -0.58 | 0.0 |
| 122739 | BRD-K07753030 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 122759 | BRD-K07753030 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122802 | BRD-K07753030 | PC3 | 1.11 uM | 24 h | 0.28 | 1.18 | 0.39 | 0.0 | 0.0 | 0.0 |
| 130873 | BRD-K07753030 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.67 |
| 130922 | BRD-K07753030 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130943 | BRD-K07753030 | HEK293 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 130979 | BRD-K07753030 | HELA | 0.03 uM | 24 h | 0.25 | 1.03 | 0.13 | 0.19 | 0.68 | 0.01 |
| 131007 | BRD-K07753030 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131061 | BRD-K07753030 | HUVEC | 0.08 uM | 24 h | 0.29 | 1.22 | 0.48 | 0.31 | 1.1 | 0.69 |
| 131131 | BRD-K07753030 | MDAMB231 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131193 | BRD-K07753030 | YAPC | 0.74 uM | 24 h | 0.25 | 1.03 | 0.14 | 0.29 | 1.04 | 0.54 |