CMap Candidate Details
Structure:
| CMap ID: | C05516 |
| Pert ID: | BRD-K17849083 |
| Compound Name: | tranilast |
| Targets: | HPGDS|HRH1 |
| MoA: | angiogenesis inhibitor |
| SMILES: | COc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24752 | BRD-K17849083 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25332 | BRD-K17849083 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52449 | BRD-K17849083 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.95 | 0.31 |
| 53009 | BRD-K17849083 | HEPG2 | 100 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 53102 | BRD-K17849083 | MCF10A | 30 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91106 | BRD-K17849083 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120293 | BRD-K17849083 | A549 | 0.37 uM | 24 h | 0.23 | 0.94 | 0.06 | 0.0 | 0.0 | 0.0 |
| 120417 | BRD-K17849083 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.1 | 0.69 |
| 120493 | BRD-K17849083 | YAPC | 0.04 uM | 24 h | 0.26 | 1.1 | 0.24 | 0.0 | 0.0 | 0.0 |
| 128895 | BRD-K17849083 | A375 | 0.03 uM | 24 h | -0.27 | -1.14 | 0.43 | 0.0 | 0.0 | 0.0 |
| 128929 | BRD-K17849083 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128956 | BRD-K17849083 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |