CMap Candidate Details
Structure:
| CMap ID: | C05525 |
| Pert ID: | BRD-K23976833 |
| Compound Name: | travoprost |
| Targets: | PTGFR |
| MoA: | prostanoid receptor agonist |
| SMILES: | CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1cccc(c1)C(F)(F)F |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120891 | BRD-K23976833 | A549 | 0.125 uM | 24 h | -0.29 | -1.21 | 0.6 | -0.33 | -1.12 | 0.94 |
| 120917 | BRD-K23976833 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120967 | BRD-K23976833 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121054 | BRD-K23976833 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.06 | 0.58 |
| 121124 | BRD-K23976833 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129100 | BRD-K23976833 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.06 |
| 129154 | BRD-K23976833 | HELA | 0.08 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 129200 | BRD-K23976833 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129226 | BRD-K23976833 | PC3 | 0.74 uM | 24 h | 0.19 | 0.79 | 0.0 | 0.0 | 0.0 | 0.0 |