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CMap Candidate Details

Structure:
CMap ID: C05552
Pert ID: BRD-K80431395
Compound Name: triciribine
Targets: AKT1|AKT2|AKT3
MoA: AKT inhibitor
SMILES: Cn1nc(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5231 BRD-K80431395 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
6299 BRD-K80431395 PC3 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.43 15.35
6430 BRD-K80431395 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45037 BRD-K80431395 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45326 BRD-K80431395 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45584 BRD-K80431395 HT29 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.16 1.11
46149 BRD-K80431395 NPC 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
46464 BRD-K80431395 PHH 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.52 15.35
46790 BRD-K80431395 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97736 BRD-K80431395 NKDBA 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
116024 BRD-K80431395 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.26
116063 BRD-K80431395 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116106 BRD-K80431395 HCC515 10 uM 24 h 0.29 1.23 0.49 0.0 0.0 0.0
116233 BRD-K80431395 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).