Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C05555
Pert ID: BRD-K41731458
Compound Name: triclosan
Targets: DNMT1
MoA: antibacterial agent
SMILES: Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5628 BRD-K41731458 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.34
6387 BRD-K41731458 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37156 BRD-K41731458 A375 10 uM 6 h -0.31 -1.29 0.77 0.0 0.0 0.0
37385 BRD-K41731458 A549 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
37655 BRD-K41731458 ASC 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
38480 BRD-K41731458 NPC 10 uM 24 h 0.23 0.94 0.06 -0.28 -0.96 0.42
38720 BRD-K41731458 PHH 10 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
38954 BRD-K41731458 SKB 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.72
52966 BRD-K41731458 HEPG2 40 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
53238 BRD-K41731458 MCF10A 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123605 BRD-K41731458 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123670 BRD-K41731458 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123737 BRD-K41731458 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123781 BRD-K41731458 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132026 BRD-K41731458 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
132053 BRD-K41731458 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132128 BRD-K41731458 PC3 2.22 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).