CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05558
Pert ID:	BRD-K89732114
Compound Name:	trifluoperazine
Targets:	ADRA1A\|CALM1\|CALY\|DRD2\|DRD4\|HRH1\|HTR2A\|HTR2C\|S100A4\|TNNC1
MoA:	dopamine receptor antagonist
SMILES:	CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8029	BRD-K89732114	HT29	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.05	0.7
9252	BRD-K89732114	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9539	BRD-K89732114	AGS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9846	BRD-K89732114	H1299	10 uM	6 h	0.0	0.0	0.0	0.24	0.86	0.16
10622	BRD-K89732114	HCT116	10 uM	6 h	0.0	0.0	0.0	0.31	1.1	0.68
11606	BRD-K89732114	NCIH2073	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11865	BRD-K89732114	NCIH508	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12163	BRD-K89732114	NCIH596	10 uM	6 h	0.0	0.0	0.0	0.25	0.9	0.22
12401	BRD-K89732114	NOMO1	10 uM	6 h	0.0	0.0	0.0	0.43	1.51	2.28
12894	BRD-K89732114	SW480	10 uM	6 h	0.25	1.02	0.13	0.0	0.0	0.0
13108	BRD-K89732114	THP1	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13389	BRD-K89732114	U937	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
88146	BRD-K89732114	VCAP	20 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91073	BRD-K89732114	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
96903	BRD-K89732114	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99106	BRD-K89732114	NEU	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
99258	BRD-K89732114	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
114319	BRD-K89732114	U2OS	20 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
116276	BRD-K89732114	A375	10 uM	24 h	0.23	0.95	0.06	0.0	0.0	0.0
116363	BRD-K89732114	HA1E	10 uM	24 h	0.0	0.0	0.0	0.34	1.2	1.11
116407	BRD-K89732114	HCC515	10 uM	24 h	0.18	0.74	0.0	0.0	0.0	0.0
116456	BRD-K89732114	HEPG2	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116557	BRD-K89732114	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121646	BRD-K89732114	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121711	BRD-K89732114	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary