CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05570
Pert ID:	BRD-K34415467
Compound Name:	trimethobenzamide
Targets:	DRD2
MoA:	histamine receptor antagonist
SMILES:	COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4418	BRD-K34415467	HCC515	10 uM	24 h	0.18	0.74	0.0	0.0	0.0	0.0
5076	BRD-K34415467	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.24	-0.82	0.15
37145	BRD-K34415467	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37282	BRD-K34415467	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37639	BRD-K34415467	ASC	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	0.98
38465	BRD-K34415467	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38711	BRD-K34415467	PHH	10 uM	24 h	0.23	0.96	0.08	0.0	0.0	0.0
121789	BRD-K34415467	HT29	1.11 uM	24 h	-0.22	-0.93	0.07	0.0	0.0	0.0
129784	BRD-K34415467	HA1E	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129818	BRD-K34415467	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.29	1.03	0.5
129868	BRD-K34415467	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129945	BRD-K34415467	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129993	BRD-K34415467	MCF??7.00	0.03 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.75
130029	BRD-K34415467	MDAMB231	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130077	BRD-K34415467	PC3	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130101	BRD-K34415467	THP1	0.08 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.72
130150	BRD-K34415467	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary