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CMap Candidate Details

Structure:
CMap ID: C05577
Pert ID: BRD-K57033106
Compound Name: tripelennamine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: CN(C)CCN(Cc1ccccc1)c1ccccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4122 BRD-K57033106 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4445 BRD-K57033106 HCC515 10 uM 24 h 0.28 1.15 0.32 0.0 0.0 0.0
4697 BRD-K57033106 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24687 BRD-K57033106 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25098 BRD-K57033106 MCF??7.00 10 uM 6 h 0.21 0.87 0.01 -0.28 -0.95 0.39
25395 BRD-K57033106 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37175 BRD-K57033106 A375 10 uM 6 h -0.25 -1.04 0.22 -0.32 -1.07 0.76
37698 BRD-K57033106 ASC 10 uM 24 h -0.32 -1.34 0.97 -0.24 -0.8 0.12
37925 BRD-K57033106 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38098 BRD-K57033106 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38519 BRD-K57033106 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38749 BRD-K57033106 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38977 BRD-K57033106 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99688 BRD-K57033106 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).