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CMap Candidate Details

Structure:
CMap ID: C05578
Pert ID: BRD-K11742128
Compound Name: triprolidine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: Cc1ccc(cc1)C(=C/CN1CCCC1)\c1ccccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6724 BRD-K11742128 A375 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
7139 BRD-K11742128 A549 10 uM 6 h -0.25 -1.04 0.21 -0.32 -1.07 0.78
7426 BRD-K11742128 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7624 BRD-K11742128 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7835 BRD-K11742128 HT29 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
8077 BRD-K11742128 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8492 BRD-K11742128 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8646 BRD-K11742128 VCAP 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
91137 BRD-K11742128 HUH7 12 uM 72 h 0.0 0.0 0.0 -0.25 -0.85 0.19
100083 BRD-K11742128 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).