CMap Candidate Details
Structure:
| CMap ID: | C05580 |
| Pert ID: | BRD-K39484304 |
| Compound Name: | triptolide |
| Targets: | RELA |
| MoA: | RNA polymerase inhibitor |
| SMILES: | CC(C)[C@]12O[C@H]1[C@@H]1O[C@]11[C@]3(O[C@H]3C[C@H]3C4=C(CC[C@]13C)C(=O)OC4)[C@@H]2O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24433 | BRD-K39484304 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.41 | 1.45 | 2.22 |
| 24667 | BRD-K39484304 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.84 | 0.13 |
| 24770 | BRD-K39484304 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.37 | 1.32 | 1.61 |
| 24899 | BRD-K39484304 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.09 |
| 25018 | BRD-K39484304 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25158 | BRD-K39484304 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25507 | BRD-K39484304 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99923 | BRD-K39484304 | U2OS | 15 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.06 | 0.59 |