CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05589
Pert ID:	BRD-A84389633
Compound Name:	tropanyl-3,5-dimethylbenzoate
Targets:	HTR3A\|HTR3B
MoA:	serotonin receptor antagonist
SMILES:	CN1C2CCC1CC(C2)OC(=O)c1cc(C)cc(C)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2822	BRD-A84389633	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3122	BRD-A84389633	HCC515	10 uM	24 h	-0.29	-1.23	0.62	0.27	0.94	0.29
3455	BRD-A84389633	PC3	10 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
3705	BRD-A84389633	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39075	BRD-A84389633	A375	10 uM	6 h	0.2	0.85	0.0	0.0	0.0	0.0
39414	BRD-A84389633	A549	10 uM	6 h	0.0	0.0	0.0	-0.32	-1.08	0.78
39602	BRD-A84389633	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39922	BRD-A84389633	HEPG2	10 uM	6 h	0.27	1.12	0.26	-0.22	-0.75	0.06
40207	BRD-A84389633	HT29	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.96	0.44
40582	BRD-A84389633	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40725	BRD-A84389633	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41027	BRD-A84389633	NPC	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.3	1.6
41350	BRD-A84389633	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
100360	BRD-A84389633	U2OS	10 uM	6 h	0.0	0.0	0.0	0.26	0.92	0.25

Summary