Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00559
Pert ID: BRD-K74501079
Compound Name: azithromycin
Targets: MLNR
MoA: bacterial 50S ribosomal subunit inhibitor
SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19128 BRD-K74501079 A375 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.74
19497 BRD-K74501079 A549 10 uM 6 h -0.22 -0.94 0.07 0.0 0.0 0.0
19775 BRD-K74501079 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20101 BRD-K74501079 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.21
20435 BRD-K74501079 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20748 BRD-K74501079 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20948 BRD-K74501079 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21302 BRD-K74501079 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21788 BRD-K74501079 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
91391 BRD-K74501079 HUH7 4 uM 72 h 0.29 1.2 0.43 -0.3 -1.0 0.54
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).