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CMap Candidate Details

Structure:
CMap ID: C05620
Pert ID: BRD-K68336408
Compound Name: tyrphostin-AG-1478
Targets: EGFR|MAPK14
MoA: EGFR inhibitor
SMILES: COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1772 BRD-K68336408 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1952 BRD-K68336408 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9029 BRD-K68336408 A375 60 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.39
9484 BRD-K68336408 AGS 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9789 BRD-K68336408 H1299 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10829 BRD-K68336408 HEPG2 60 uM 6 h 0.19 0.78 0.0 -0.39 -1.31 1.71
11071 BRD-K68336408 HT29 60 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
11291 BRD-K68336408 MCF??7.00 60 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.03
11550 BRD-K68336408 NCIH2073 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11816 BRD-K68336408 NCIH508 60 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
12108 BRD-K68336408 NCIH596 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12366 BRD-K68336408 NOMO1 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12621 BRD-K68336408 PC3 60 uM 6 h 0.22 0.9 0.02 -0.27 -0.92 0.32
12847 BRD-K68336408 SW480 60 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.02
12989 BRD-K68336408 THP1 60 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.62
13335 BRD-K68336408 U937 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13663 BRD-K68336408 VCAP 60 uM 6 h 0.17 0.72 0.0 -0.31 -1.05 0.7
42133 BRD-K68336408 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43927 BRD-K68336408 PHH 10 uM 24 h 0.31 1.27 0.59 0.0 0.0 0.0
44183 BRD-K68336408 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92927 BRD-K68336408 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92989 BRD-K68336408 CD34 10 uM 24 h -0.24 -1.01 0.17 -0.26 -0.89 0.26
93077 BRD-K68336408 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
93121 BRD-K68336408 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93214 BRD-K68336408 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93271 BRD-K68336408 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
93311 BRD-K68336408 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
93352 BRD-K68336408 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
93391 BRD-K68336408 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93479 BRD-K68336408 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93578 BRD-K68336408 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99384 BRD-K68336408 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).