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CMap Candidate Details

Structure:
CMap ID: C05624
Pert ID: BRD-K17415526
Compound Name: tyrphostin-AG-835
Targets: EGFR
MoA: protein tyrosine kinase inhibitor
SMILES: C[C@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4073 BRD-K17415526 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4380 BRD-K17415526 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4655 BRD-K17415526 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
5047 BRD-K17415526 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
44323 BRD-K17415526 A375 10 uM 6 h 0.2 0.83 0.0 0.0 0.0 0.0
44534 BRD-K17415526 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
44880 BRD-K17415526 ASC 10 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
45182 BRD-K17415526 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45450 BRD-K17415526 HT29 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.39 2.02
45660 BRD-K17415526 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45997 BRD-K17415526 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.62
46315 BRD-K17415526 PHH 10 uM 24 h 0.27 1.15 0.32 0.0 0.0 0.0
46630 BRD-K17415526 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100159 BRD-K17415526 U2OS 10 uM 6 h -0.23 -0.97 0.11 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).