CMap Candidate Details
Structure:
| CMap ID: | C05625 |
| Pert ID: | BRD-K59469039 |
| Compound Name: | tyrphostin-AG-879 |
| Targets: | ERBB2|KDR|NTRK1 |
| MoA: | tyrosine kinase inhibitor |
| SMILES: | CC(C)(C)c1cc(cc(c1O)C(C)(C)C)\C=C(/C#N)C(N)=S |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1591 | BRD-K59469039 | HA1E | 10 uM | 24 h | 0.25 | 1.06 | 0.18 | 0.0 | 0.0 | 0.0 |
| 1928 | BRD-K59469039 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 2168 | BRD-K59469039 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.3 | 1.58 |
| 2651 | BRD-K59469039 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.62 |
| 41795 | BRD-K59469039 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42110 | BRD-K59469039 | A549 | 10 uM | 6 h | -0.22 | -0.9 | 0.04 | 0.0 | 0.0 | 0.0 |
| 42402 | BRD-K59469039 | ASC | 10 uM | 24 h | -0.24 | -0.98 | 0.12 | -0.3 | -1.0 | 0.55 |
| 43021 | BRD-K59469039 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43207 | BRD-K59469039 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.33 | 1.72 |
| 43586 | BRD-K59469039 | NPC | 10 uM | 24 h | 0.26 | 1.1 | 0.24 | -0.3 | -1.03 | 0.62 |
| 53405 | BRD-K59469039 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53524 | BRD-K59469039 | HUH7 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.27 |
| 53677 | BRD-K59469039 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99705 | BRD-K59469039 | U2OS | 15 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.01 |