CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05627
Pert ID:	BRD-K40255344
Compound Name:	tyrphostin-A9
Targets:
MoA:	protein tyrosine kinase inhibitor; tyrosine kinase inhibitor
SMILES:	CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33694	BRD-K40255344	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
33904	BRD-K40255344	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34101	BRD-K40255344	ASC	10 uM	24 h	0.27	1.14	0.32	-0.42	-1.42	15.35
34362	BRD-K40255344	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34618	BRD-K40255344	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.36	-1.21	1.24
34884	BRD-K40255344	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35145	BRD-K40255344	HT29	10 uM	6 h	0.0	0.0	0.0	-0.42	-1.4	2.02
35466	BRD-K40255344	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.34	-1.15	1.07
35568	BRD-K40255344	NEU	10 uM	24 h	0.21	0.88	0.01	0.36	1.27	1.34
35782	BRD-K40255344	NPC	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.74
35959	BRD-K40255344	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36560	BRD-K40255344	SKB	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.61
36967	BRD-K40255344	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.04	0.66
53585	BRD-K40255344	HUH7	10 uM	6 h	-0.22	-0.92	0.06	-0.44	-1.48	15.35
53661	BRD-K40255344	PHH	10 uM	24 h	0.17	0.71	0.0	-0.35	-1.17	1.12
99929	BRD-K40255344	U2OS	20 uM	6 h	0.0	0.0	0.0	-0.32	-1.07	0.76

Summary