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CMap Candidate Details

Structure:
CMap ID: C05644
Pert ID: BRD-K50325075
Compound Name: UCL-2077
Targets:
MoA: slow afterhyperpolarization channel blocker
SMILES: C(NC(c1ccccc1)(c1ccccc1)c1ccccc1)c1cccnc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3035 BRD-K50325075 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
3221 BRD-K50325075 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3519 BRD-K50325075 PC3 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
3819 BRD-K50325075 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41779 BRD-K50325075 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41942 BRD-K50325075 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
42378 BRD-K50325075 ASC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
42699 BRD-K50325075 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.43
43002 BRD-K50325075 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
43324 BRD-K50325075 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43566 BRD-K50325075 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43866 BRD-K50325075 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44127 BRD-K50325075 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99615 BRD-K50325075 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).