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CMap Candidate Details

Structure:
CMap ID: C05649
Pert ID: BRD-K06294530
Compound Name: UK-383367
Targets: BMP1
MoA: Procollagen C-Endopeptidase Inhibitors
SMILES: NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122543 BRD-K06294530 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122575 BRD-K06294530 A549 10 uM 24 h 0.28 1.18 0.39 -0.29 -0.99 0.5
122658 BRD-K06294530 HELA 10 uM 24 h 0.22 0.92 0.04 -0.26 -0.88 0.25
122716 BRD-K06294530 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122751 BRD-K06294530 MCF??7.00 10 uM 24 h 0.2 0.82 0.0 0.26 0.93 0.26
122771 BRD-K06294530 MDAMB231 10 uM 24 h -0.23 -0.97 0.11 0.27 0.95 0.31
130911 BRD-K06294530 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130933 BRD-K06294530 HEK293 2.22 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
130996 BRD-K06294530 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
131038 BRD-K06294530 HUVEC 0.03 uM 24 h -0.28 -1.18 0.5 -0.3 -1.0 0.51
131148 BRD-K06294530 PC3 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
131181 BRD-K06294530 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).