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CMap Candidate Details

Structure:
CMap ID: C05661
Pert ID: BRD-K86856088
Compound Name: UNC0638
Targets: EHMT1|EHMT2
MoA: histone lysine methyltransferase inhibitor
SMILES: COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)C1CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93624 BRD-K86856088 A549 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93665 BRD-K86856088 ASC 10 uM 24 h 0.23 0.96 0.07 0.29 1.01 0.45
93730 BRD-K86856088 CD34 10 uM 24 h 0.36 1.49 1.17 0.0 0.0 0.0
93766 BRD-K86856088 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93805 BRD-K86856088 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93855 BRD-K86856088 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93896 BRD-K86856088 HELA 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
93938 BRD-K86856088 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93969 BRD-K86856088 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94039 BRD-K86856088 JURKAT 3.33 uM 24 h -0.29 -1.19 0.53 0.0 0.0 0.0
94069 BRD-K86856088 MCF??7.00 10 uM 24 h -0.29 -1.19 0.53 -0.39 -1.3 1.57
94120 BRD-K86856088 NEU 10 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
94180 BRD-K86856088 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94199 BRD-K86856088 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94254 BRD-K86856088 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94305 BRD-K86856088 SKL 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.7
94349 BRD-K86856088 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94388 BRD-K86856088 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96831 BRD-K86856088 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).