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CMap Candidate Details

Structure:
CMap ID: C05669
Pert ID: BRD-K21906513
Compound Name: UNC669
Targets: L3MBTL1
MoA: L3MBTL antagonist
SMILES: Brc1cncc(c1)C(=O)N1CCC(CC1)N1CCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93615 BRD-K21906513 A549 0.12 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
93651 BRD-K21906513 ASC 1.11 uM 24 h -0.26 -1.09 0.31 -0.31 -1.04 0.66
93711 BRD-K21906513 CD34 0.12 uM 24 h -0.29 -1.21 0.58 0.0 0.0 0.0
93757 BRD-K21906513 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93791 BRD-K21906513 HCC515 3.33 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
93838 BRD-K21906513 HEK293 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
93884 BRD-K21906513 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93924 BRD-K21906513 HEPG2 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93959 BRD-K21906513 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
94022 BRD-K21906513 JURKAT 3.33 uM 24 h -0.18 -0.73 0.0 0.0 0.0 0.0
94060 BRD-K21906513 MCF??7.00 10 uM 24 h -0.19 -0.79 0.0 0.29 1.01 0.46
94102 BRD-K21906513 NEU 1.11 uM 24 h -0.29 -1.21 0.59 0.0 0.0 0.0
94137 BRD-K21906513 NPC 10 uM 24 h 0.3 1.24 0.53 -0.35 -1.16 1.11
94191 BRD-K21906513 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94235 BRD-K21906513 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
94286 BRD-K21906513 SKL 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
94335 BRD-K21906513 THP1 3.33 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
94379 BRD-K21906513 YAPC 0.04 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
96628 BRD-K21906513 A375 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).