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CMap Candidate Details

Structure:
CMap ID: C05700
Pert ID: BRD-K45158365
Compound Name: valsartan
Targets: AGTR1
MoA: angiotensin receptor antagonist
SMILES: CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1)[C@@H](C(C)C)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4433 BRD-K45158365 HCC515 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
5087 BRD-K45158365 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37666 BRD-K45158365 ASC 10 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
38491 BRD-K45158365 NPC 10 uM 24 h -0.31 -1.29 0.8 -0.3 -1.01 0.56
38729 BRD-K45158365 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95300 BRD-K45158365 A549 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99557 BRD-K45158365 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
125231 BRD-K45158365 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125270 BRD-K45158365 HA1E 10 uM 24 h 0.25 1.04 0.14 -0.27 -0.91 0.31
125294 BRD-K45158365 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
125346 BRD-K45158365 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125430 BRD-K45158365 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
125484 BRD-K45158365 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125541 BRD-K45158365 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
133442 BRD-K45158365 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133473 BRD-K45158365 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133504 BRD-K45158365 MCF10A 2.22 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
133539 BRD-K45158365 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133594 BRD-K45158365 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).