CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05707
Pert ID:	BRD-K32501161
Compound Name:	vanoxerine
Targets:	SLC6A3
MoA:	dopamine uptake inhibitor
SMILES:	Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2864	BRD-K32501161	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3175	BRD-K32501161	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3484	BRD-K32501161	PC3	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.38	2.02
3767	BRD-K32501161	VCAP	10 uM	24 h	-0.18	-0.74	0.0	-0.32	-1.09	0.81
44563	BRD-K32501161	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44925	BRD-K32501161	ASC	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.38
45225	BRD-K32501161	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45682	BRD-K32501161	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.48
46360	BRD-K32501161	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
98369	BRD-K32501161	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
98687	BRD-K32501161	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
99844	BRD-K32501161	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
120520	BRD-K32501161	A375	10 uM	24 h	0.24	1.0	0.11	-0.3	-1.02	0.6
120618	BRD-K32501161	HELA	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.12	0.94
120655	BRD-K32501161	HT29	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120707	BRD-K32501161	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120814	BRD-K32501161	YAPC	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.8

Summary