CMap Candidate Details
Structure:
| CMap ID: | C05710 |
| Pert ID: | BRD-K09711437 |
| Compound Name: | varespladib |
| Targets: | PLA2G2A |
| MoA: | secretory phospholipase inhibitor |
| SMILES: | CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121192 | BRD-K09711437 | A549 | 3.33 uM | 24 h | 0.27 | 1.14 | 0.32 | 0.0 | 0.0 | 0.0 |
| 121253 | BRD-K09711437 | HELA | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121320 | BRD-K09711437 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129247 | BRD-K09711437 | A375 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129255 | BRD-K09711437 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.64 | 0.01 |
| 129302 | BRD-K09711437 | HT29 | 0.03 uM | 24 h | -0.22 | -0.93 | 0.07 | -0.37 | -1.24 | 1.3 |
| 129338 | BRD-K09711437 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.26 | 1.29 |
| 129376 | BRD-K09711437 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.17 | -0.58 | 0.0 |