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CMap Candidate Details

Structure:
CMap ID: C05719
Pert ID: BRD-K12737986
Compound Name: veliparib
Targets: PARP1|PARP2
MoA: PARP inhibitor
SMILES: C[C@]1(CCCN1)c1nc2c(cccc2[nH]1)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90845 BRD-K12737986 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96460 BRD-K12737986 A375 10 uM 24 h -0.18 -0.75 0.0 0.31 1.11 0.72
122280 BRD-K12737986 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122381 BRD-K12737986 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122460 BRD-K12737986 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122508 BRD-K12737986 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130581 BRD-K12737986 HA1E 0.03 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
130613 BRD-K12737986 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
130653 BRD-K12737986 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130694 BRD-K12737986 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.77
130777 BRD-K12737986 MDAMB231 2.22 uM 24 h 0.26 1.07 0.19 0.3 1.06 0.58
130806 BRD-K12737986 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).