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CMap Candidate Details

Structure:
CMap ID: C05724
Pert ID: BRD-K32330832
Compound Name: VER-155008
Targets: HSPA1A
MoA: HSP inhibitor
SMILES: Nc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C#N)[C@@H](O)[C@H]3O)c(NCc3ccc(Cl)c(Cl)c3)nc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8933 BRD-K32330832 A375 12 uM 24 h 0.0 0.0 0.0 -0.58 -1.97 15.65
9096 BRD-K32330832 A549 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9408 BRD-K32330832 AGS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9715 BRD-K32330832 H1299 12 uM 6 h 0.24 1.02 0.12 0.0 0.0 0.0
10372 BRD-K32330832 HCC515 12 uM 6 h -0.2 -0.84 0.01 0.42 1.48 2.24
10502 BRD-K32330832 HCT116 12 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.29
10774 BRD-K32330832 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
10967 BRD-K32330832 HT29 12 uM 24 h 0.14 0.6 0.0 0.26 0.93 0.28
11470 BRD-K32330832 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11749 BRD-K32330832 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12033 BRD-K32330832 NCIH596 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12571 BRD-K32330832 PC3 12 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
13116 BRD-K32330832 THP1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13258 BRD-K32330832 U937 12 uM 6 h 0.0 0.0 0.0 0.35 1.24 1.28
13612 BRD-K32330832 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96050 BRD-K32330832 PHH 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
98004 BRD-K32330832 HA1E 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98037 BRD-K32330832 MCF??7.00 12 uM 24 h -0.2 -0.82 0.0 -0.27 -0.89 0.27
98088 BRD-K32330832 P1A82 12 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).