CMap Candidate Details
Structure:
| CMap ID: | C05730 |
| Pert ID: | BRD-K19741547 |
| Compound Name: | vernakalant |
| Targets: | KCNA5 |
| MoA: | potassium channel blocker |
| SMILES: | COc1ccc(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121363 | BRD-K19741547 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121383 | BRD-K19741547 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.25 |
| 121505 | BRD-K19741547 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.13 | 0.99 |
| 129464 | BRD-K19741547 | HELA | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129486 | BRD-K19741547 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129516 | BRD-K19741547 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129549 | BRD-K19741547 | PC3 | 2.22 uM | 24 h | 0.31 | 1.27 | 0.58 | 0.0 | 0.0 | 0.0 |