CMap Candidate Details
Structure:
| CMap ID: | C05735 |
| Pert ID: | BRD-A32269193 |
| Compound Name: | VGX-1027 |
| Targets: | TLR4 |
| MoA: | tumor necrosis factor receptor antagonist |
| SMILES: | OC(=O)CC1CC(=NO1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120519 | BRD-A32269193 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.48 |
| 120554 | BRD-A32269193 | A549 | 0.37 uM | 24 h | -0.19 | -0.77 | 0.0 | 0.29 | 1.03 | 0.51 |
| 120594 | BRD-A32269193 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120634 | BRD-A32269193 | HELA | 10 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120654 | BRD-A32269193 | HT29 | 0.04 uM | 24 h | -0.26 | -1.1 | 0.34 | -0.26 | -0.88 | 0.25 |
| 120751 | BRD-A32269193 | MCF??7.00 | 1.11 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.31 | 1.1 | 0.7 |
| 120813 | BRD-A32269193 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 129078 | BRD-A32269193 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |