CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05740
Pert ID:	BRD-K58010567
Compound Name:	vilazodone
Targets:	DRD2\|DRD3\|HRH1\|HTR1A\|HTR4\|SLC6A4
MoA:	serotonin reuptake inhibitor
SMILES:	NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123798	BRD-K58010567	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123838	BRD-K58010567	A549	0.04 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.86
123903	BRD-K58010567	HEK293	10 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.39
123967	BRD-K58010567	HT29	10 uM	24 h	0.0	0.0	0.0	0.42	1.47	2.24
124004	BRD-K58010567	JURKAT	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124057	BRD-K58010567	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124186	BRD-K58010567	THP1	0.125 uM	24 h	0.0	0.0	0.0	-0.25	-0.85	0.19
124238	BRD-K58010567	YAPC	10 uM	24 h	0.33	1.37	0.97	0.0	0.0	0.0
132166	BRD-K58010567	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132198	BRD-K58010567	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132254	BRD-K58010567	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	-0.37	-1.24	1.35
132276	BRD-K58010567	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132297	BRD-K58010567	PC3	0.74 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.41

Summary