CMap Candidate Details
Structure:
| CMap ID: | C05763 |
| Pert ID: | BRD-K23677682 |
| Compound Name: | voreloxin |
| Targets: | TOP2A |
| MoA: | topoisomerase inhibitor |
| SMILES: | CN[C@H]1CN(C[C@@H]1OC)c1ccc2c(n1)n(cc(C(O)=O)c2=O)-c1nccs1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120868 | BRD-K23677682 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120959 | BRD-K23677682 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120987 | BRD-K23677682 | HELA | 10 uM | 24 h | 0.3 | 1.23 | 0.5 | 0.0 | 0.0 | 0.0 |
| 121047 | BRD-K23677682 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.25 |
| 121080 | BRD-K23677682 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 121115 | BRD-K23677682 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129118 | BRD-K23677682 | A549 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129138 | BRD-K23677682 | HA1E | 2.22 uM | 24 h | -0.18 | -0.73 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129193 | BRD-K23677682 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.31 |