CMap Candidate Details
Structure:
| CMap ID: | C05813 |
| Pert ID: | BRD-K07487750 |
| Compound Name: | WHI-P154 |
| Targets: | EGFR|JAK1|JAK2|JAK3 |
| MoA: | JAK inhibitor |
| SMILES: | COc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90875 | BRD-K07487750 | MCF10A | 1.11 uM | 3 h | 0.24 | 0.99 | 0.1 | 0.37 | 1.32 | 1.59 |
| 96454 | BRD-K07487750 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96522 | BRD-K07487750 | PC3 | 10 uM | 24 h | 0.19 | 0.8 | 0.0 | -0.34 | -1.13 | 0.98 |