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CMap Candidate Details

Structure:
CMap ID: C05829
Pert ID: BRD-K73293050
Compound Name: WZ-3146
Targets: EGFR
MoA: EGFR inhibitor
SMILES: CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33578 BRD-K73293050 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33833 BRD-K73293050 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34166 BRD-K73293050 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34410 BRD-K73293050 HA1E 10 uM 6 h 0.0 0.0 0.0 0.36 1.29 1.49
34672 BRD-K73293050 HCC515 10 uM 6 h 0.0 0.0 0.0 0.4 1.43 2.2
34946 BRD-K73293050 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35190 BRD-K73293050 HT29 10 uM 6 h -0.27 -1.12 0.38 0.0 0.0 0.0
35340 BRD-K73293050 MCF??7.00 10 uM 24 h 0.23 0.97 0.08 -0.22 -0.75 0.07
35612 BRD-K73293050 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35830 BRD-K73293050 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35992 BRD-K73293050 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36337 BRD-K73293050 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36633 BRD-K73293050 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
36863 BRD-K73293050 VCAP 10 uM 24 h 0.15 0.64 0.0 0.24 0.85 0.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).