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CMap Candidate Details

Structure:
CMap ID: C05854
Pert ID: BRD-K21565985
Compound Name: xylazine
Targets: ADRA2A|ADRA2B|ADRA2C
MoA: adrenergic receptor agonist
SMILES: Cc1cccc(C)c1NC1=NCCCS1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4203 BRD-K21565985 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4391 BRD-K21565985 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5055 BRD-K21565985 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37131 BRD-K21565985 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37274 BRD-K21565985 A549 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
37613 BRD-K21565985 ASC 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.85
38063 BRD-K21565985 HT29 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
38443 BRD-K21565985 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38698 BRD-K21565985 PHH 10 uM 24 h -0.21 -0.86 0.02 0.28 0.99 0.4
51708 BRD-K21565985 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
51925 BRD-K21565985 PC3 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
99746 BRD-K21565985 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).