CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05867
Pert ID:	BRD-A62182663
Compound Name:	YK-4-279
Targets:	EWSR1\|FLI1
MoA:	apoptosis inhibitor
SMILES:	COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8879	BRD-A62182663	A375	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.3	1.59
9149	BRD-A62182663	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9299	BRD-A62182663	AGS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9603	BRD-A62182663	H1299	10 uM	6 h	0.0	0.0	0.0	-0.28	-0.94	0.37
9883	BRD-A62182663	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
10126	BRD-A62182663	HCC515	10 uM	24 h	-0.25	-1.05	0.24	-0.21	-0.69	0.02
10410	BRD-A62182663	HCT116	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10678	BRD-A62182663	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.34	-1.14	1.03
10910	BRD-A62182663	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
11140	BRD-A62182663	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
11351	BRD-A62182663	NCIH2073	10 uM	6 h	-0.24	-1.01	0.16	-0.26	-0.88	0.24
11923	BRD-A62182663	NCIH596	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.97	0.45
12214	BRD-A62182663	NOMO1	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12442	BRD-A62182663	PC3	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
12675	BRD-A62182663	SW480	10 uM	6 h	-0.22	-0.92	0.06	0.0	0.0	0.0
12944	BRD-A62182663	THP1	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13158	BRD-A62182663	U937	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.97	0.45
88414	BRD-A62182663	VCAP	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary