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CMap Candidate Details

Structure:
CMap ID: C05884
Pert ID: BRD-A65615053
Compound Name: zacopride
Targets: HTR3A|HTR3B|HTR4|HTR5A
MoA: serotonin receptor antagonist
SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6674 BRD-A65615053 A375 10 uM 24 h -0.29 -1.19 0.53 0.25 0.87 0.17
6946 BRD-A65615053 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
7405 BRD-A65615053 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7576 BRD-A65615053 HCC515 10 uM 6 h -0.3 -1.25 0.71 0.24 0.84 0.13
8464 BRD-A65615053 PC3 10 uM 6 h -0.29 -1.2 0.55 -0.33 -1.1 0.86
8771 BRD-A65615053 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24852 BRD-A65615053 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25074 BRD-A65615053 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98193 BRD-A65615053 NPC 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
98510 BRD-A65615053 NEU 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
100276 BRD-A65615053 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).