CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05886
Pert ID:	BRD-K85925969
Compound Name:	zalcitabine
Targets:
MoA:	nucleoside reverse transcriptase inhibitor
SMILES:	Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25434	BRD-K85925969	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91240	BRD-K85925969	HUH7	15 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
125570	BRD-K85925969	A375	0.125 uM	24 h	-0.27	-1.11	0.36	0.32	1.15	0.89
125608	BRD-K85925969	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125641	BRD-K85925969	HEK293	3.33 uM	24 h	0.35	1.47	1.12	0.0	0.0	0.0
125719	BRD-K85925969	HUVEC	0.125 uM	24 h	-0.26	-1.07	0.27	-0.22	-0.73	0.04
125918	BRD-K85925969	YAPC	0.04 uM	24 h	0.28	1.18	0.38	0.0	0.0	0.0
133690	BRD-K85925969	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133755	BRD-K85925969	HELA	0.03 uM	24 h	0.27	1.13	0.28	0.25	0.9	0.22
133791	BRD-K85925969	HT29	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133820	BRD-K85925969	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133848	BRD-K85925969	MCF10A	0.74 uM	24 h	-0.25	-1.04	0.22	-0.3	-1.0	0.55
133878	BRD-K85925969	MCF??7.00	0.25 uM	24 h	0.23	0.96	0.07	0.29	1.03	0.51
133903	BRD-K85925969	MDAMB231	2.22 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.56
133937	BRD-K85925969	PC3	2.22 uM	24 h	0.0	0.0	0.0	0.33	1.15	0.9
133967	BRD-K85925969	THP1	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary