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CMap Candidate Details

Structure:
CMap ID: C05906
Pert ID: BRD-K72903603
Compound Name: zidovudine
Targets: TERT
MoA: nucleoside reverse transcriptase inhibitor
SMILES: Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49882 BRD-K72903603 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50046 BRD-K72903603 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50229 BRD-K72903603 HA1E 10 uM 6 h 0.0 0.0 0.0 0.33 1.19 1.01
50405 BRD-K72903603 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50577 BRD-K72903603 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.58
51057 BRD-K72903603 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51267 BRD-K72903603 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51505 BRD-K72903603 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
91314 BRD-K72903603 HUH7 12.5 uM 72 h -0.25 -1.05 0.24 0.26 0.92 0.26
99437 BRD-K72903603 U2OS 10 uM 6 h 0.32 1.35 0.94 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).