CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00591
Pert ID:	BRD-A00147595
Compound Name:	balaglitazone
Targets:	PPARG
MoA:	insulin sensitizer; PPAR receptor partial agonist
SMILES:	Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccccc2c1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
122851	BRD-A00147595	HA1E	0.04 uM	24 h	0.24	1.02	0.12	0.0	0.0	0.0
122874	BRD-A00147595	HEK293	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122958	BRD-A00147595	HT29	0.37 uM	24 h	0.0	0.0	0.0	-0.33	-1.12	0.96
122999	BRD-A00147595	JURKAT	1.11 uM	24 h	-0.33	-1.39	1.09	0.0	0.0	0.0
123051	BRD-A00147595	MCF10A	10 uM	24 h	-0.19	-0.8	0.0	-0.31	-1.04	0.68
123069	BRD-A00147595	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123088	BRD-A00147595	MDAMB231	3.33 uM	24 h	0.32	1.35	0.96	0.34	1.21	1.13
123140	BRD-A00147595	PC3	10 uM	24 h	-0.28	-1.17	0.49	-0.41	-1.4	2.02
123160	BRD-A00147595	THP1	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131197	BRD-A00147595	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131226	BRD-A00147595	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131296	BRD-A00147595	HELA	0.03 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
131336	BRD-A00147595	HUVEC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131480	BRD-A00147595	YAPC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary