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CMap Candidate Details

Structure:
CMap ID: C05925
Pert ID: BRD-K40624912
Compound Name: ZM-39923
Targets: JAK1|JAK3
MoA: JAK inhibitor
SMILES: CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6878 BRD-K40624912 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6992 BRD-K40624912 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7442 BRD-K40624912 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7651 BRD-K40624912 HCC515 10 uM 6 h 0.27 1.13 0.28 0.0 0.0 0.0
7861 BRD-K40624912 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8176 BRD-K40624912 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8366 BRD-K40624912 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8813 BRD-K40624912 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87326 BRD-K40624912 BJAB 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
87357 BRD-K40624912 HBL1 2.5 uM 24 h 0.22 0.91 0.03 0.32 1.13 0.82
87407 BRD-K40624912 K562 10 uM 24 h -0.22 -0.93 0.07 -0.31 -1.03 0.64
87455 BRD-K40624912 KMS34 0.125 uM 24 h -0.25 -1.03 0.2 -0.33 -1.12 0.93
87524 BRD-K40624912 MINO 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87559 BRD-K40624912 NALM6 0.04 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
87609 BRD-K40624912 OCILY10 0.66 uM 24 h -0.27 -1.11 0.37 -0.33 -1.1 0.88
87660 BRD-K40624912 OCILY19 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87711 BRD-K40624912 OCILY3 0.125 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
87758 BRD-K40624912 SKMEL5 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87818 BRD-K40624912 THP1 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.53
87848 BRD-K40624912 TMD8 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).