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CMap Candidate Details

Structure:
CMap ID: C05928
Pert ID: BRD-K08996725
Compound Name: zolantidine
Targets:
MoA: histamine receptor antagonist
SMILES: C(CNc1nc2ccccc2s1)COc1cccc(CN2CCCCC2)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4053 BRD-K08996725 HA1E 10 uM 24 h -0.2 -0.84 0.01 0.2 0.7 0.01
4354 BRD-K08996725 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4642 BRD-K08996725 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4888 BRD-K08996725 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44299 BRD-K08996725 A375 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.18
44518 BRD-K08996725 A549 10 uM 24 h -0.18 -0.74 0.0 0.0 0.0 0.0
44847 BRD-K08996725 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
45156 BRD-K08996725 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45423 BRD-K08996725 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45770 BRD-K08996725 MCF??7.00 10 uM 6 h -0.23 -0.96 0.09 0.0 0.0 0.0
45962 BRD-K08996725 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46282 BRD-K08996725 PHH 10 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
46597 BRD-K08996725 SKB 10 uM 24 h 0.22 0.92 0.04 0.34 1.2 1.08
100042 BRD-K08996725 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).