CMap Candidate Details
Structure:
| CMap ID: | C00593 |
| Pert ID: | BRD-K27204852 |
| Compound Name: | balicatib |
| Targets: | CTSK |
| MoA: | cathepsin inhibitor |
| SMILES: | CCCN1CCN(CC1)c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120925 | BRD-K27204852 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120981 | BRD-K27204852 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.42 | 1.49 | 2.25 |
| 121008 | BRD-K27204852 | HELA | 10 uM | 3 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 121064 | BRD-K27204852 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121138 | BRD-K27204852 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129106 | BRD-K27204852 | A375 | 0.03 uM | 24 h | 0.22 | 0.91 | 0.03 | 0.0 | 0.0 | 0.0 |
| 129125 | BRD-K27204852 | A549 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.7 |
| 129210 | BRD-K27204852 | HT29 | 0.01 uM | 24 h | -0.27 | -1.12 | 0.39 | -0.29 | -0.99 | 0.5 |
| 129238 | BRD-K27204852 | PC3 | 0.74 uM | 24 h | 0.19 | 0.79 | 0.0 | 0.0 | 0.0 | 0.0 |