CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05932
Pert ID:	BRD-K44876623
Compound Name:	zolpidem
Targets:	GABRA1\|GABRA2\|GABRA3
MoA:	benzodiazepine receptor agonist
SMILES:	CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1262	BRD-K44876623	A549	10 uM	6 h	0.28	1.15	0.33	-0.34	-1.14	1.01
1279	BRD-K44876623	MCF??7.00	0.12 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
1342	BRD-K44876623	U2OS	10 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
25372	BRD-K44876623	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
50364	BRD-K44876623	HCC515	10 uM	6 h	0.0	0.0	0.0	0.2	0.69	0.01
97128	BRD-K44876623	A375	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.41
125289	BRD-K44876623	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125364	BRD-K44876623	HT29	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125386	BRD-K44876623	JURKAT	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.84	0.17
125468	BRD-K44876623	MDAMB231	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.23
125480	BRD-K44876623	PC3	0.04 uM	24 h	-0.24	-0.98	0.13	0.0	0.0	0.0
125509	BRD-K44876623	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125537	BRD-K44876623	YAPC	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133378	BRD-K44876623	HA1E	0.03 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.72
133407	BRD-K44876623	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133500	BRD-K44876623	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary