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CMap Candidate Details

Structure:
CMap ID: C05943
Pert ID: BRD-K28761384
Compound Name: zuclopenthixol
Targets: ADRA1A|ADRA2A|DRD1|DRD2|DRD5|HRH1|HTR2A
MoA: dopamine receptor antagonist
SMILES: OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(Cl)cc23)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1575 BRD-K28761384 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1911 BRD-K28761384 HCC515 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
2303 BRD-K28761384 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41757 BRD-K28761384 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41926 BRD-K28761384 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42343 BRD-K28761384 ASC 10 uM 24 h -0.21 -0.89 0.04 -0.34 -1.14 1.03
42669 BRD-K28761384 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42974 BRD-K28761384 HT29 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
43179 BRD-K28761384 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43535 BRD-K28761384 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
90303 BRD-K28761384 VCAP 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99803 BRD-K28761384 U2OS 4 uM 6 h 0.24 1.02 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).