CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00595
Pert ID:	BRD-K41410256
Compound Name:	balsalazide
Targets:	ALOX5\|PPARG\|PTGS1\|PTGS2
MoA:	cyclooxygenase inhibitor
SMILES:	OC(=O)CCNC(=O)c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
22286	BRD-K41410256	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
22768	BRD-K41410256	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
23057	BRD-K41410256	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
24156	BRD-K41410256	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.91	0.29
95457	BRD-K41410256	U2OS	0.12 uM	6 h	0.27	1.11	0.25	0.0	0.0	0.0
123315	BRD-K41410256	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123344	BRD-K41410256	HT29	0.37 uM	24 h	0.25	1.05	0.16	-0.29	-0.97	0.46
123462	BRD-K41410256	THP1	1.11 uM	24 h	-0.32	-1.34	0.98	0.0	0.0	0.0
123496	BRD-K41410256	YAPC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131529	BRD-K41410256	A375	0.01 uM	24 h	0.0	0.0	0.0	-0.27	-0.92	0.32
131591	BRD-K41410256	HA1E	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131632	BRD-K41410256	HEK293	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131730	BRD-K41410256	HUVEC	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
131784	BRD-K41410256	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131827	BRD-K41410256	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.64
131861	BRD-K41410256	MCF??7.00	0.74 uM	24 h	-0.29	-1.22	0.61	0.0	0.0	0.0
131896	BRD-K41410256	MDAMB231	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131918	BRD-K41410256	PC3	2.22 uM	24 h	0.0	0.0	0.0	-0.43	-1.45	15.35

Summary