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CMap Candidate Details

Structure:
CMap ID: C05972
Pert ID: BRD-K92301463
Compound Name: 16,16-dimethylprostaglandin-e2
Targets: HPGD
MoA: prostanoid receptor agonist
SMILES: CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9545 BRD-K92301463 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9852 BRD-K92301463 H1299 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
10327 BRD-K92301463 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10626 BRD-K92301463 HCT116 10 uM 6 h 0.21 0.87 0.01 0.24 0.86 0.16
10877 BRD-K92301463 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11869 BRD-K92301463 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12168 BRD-K92301463 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.24
12406 BRD-K92301463 NOMO1 10 uM 6 h -0.32 -1.34 0.98 -0.34 -1.14 1.05
12901 BRD-K92301463 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13396 BRD-K92301463 U937 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
13515 BRD-K92301463 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128096 BRD-K92301463 A375 1.11 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
128158 BRD-K92301463 HEK293 1.11 uM 24 h 0.22 0.93 0.04 0.0 0.0 0.0
128197 BRD-K92301463 MCF10A 0.004 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128275 BRD-K92301463 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128343 BRD-K92301463 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
135766 BRD-K92301463 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135787 BRD-K92301463 HA1E 0.025 uM 24 h 0.33 1.36 0.97 0.0 0.0 0.0
135871 BRD-K92301463 HELA 0.001 uM 24 h -0.31 -1.28 0.77 0.0 0.0 0.0
135925 BRD-K92301463 HT29 0.22 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
135959 BRD-K92301463 JURKAT 0.001 uM 24 h -0.3 -1.23 0.64 0.0 0.0 0.0
136015 BRD-K92301463 MCF??7.00 0.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136042 BRD-K92301463 PC3 0.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
136105 BRD-K92301463 YAPC 0.22 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).