CMap Candidate Details
Structure:
| CMap ID: | C06005 |
| Pert ID: | BRD-K07954936 |
| Compound Name: | 2-iminobiotin |
| Targets: | NOS1|NOS2 |
| MoA: | nitric oxide synthase inhibitor |
| SMILES: | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=N)N[C@H]12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121141 | BRD-K07954936 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121176 | BRD-K07954936 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121211 | BRD-K07954936 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.73 |
| 121262 | BRD-K07954936 | HELA | 3.33 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121301 | BRD-K07954936 | PC3 | 0.37 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.0 | 0.0 | 0.0 |
| 121340 | BRD-K07954936 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129286 | BRD-K07954936 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129323 | BRD-K07954936 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.25 |