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CMap Candidate Details

Structure:
CMap ID: C06037
Pert ID: BRD-K92980438
Compound Name: 3-bromopyruvate
Targets: HK2
MoA: hexokinase inhibitor
SMILES: OC(=O)C(=O)CBr
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9008 BRD-K92980438 A375 150 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
9126 BRD-K92980438 A549 150 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.68
9547 BRD-K92980438 AGS 150 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.37
10095 BRD-K92980438 HA1E 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10280 BRD-K92980438 HCC515 150 uM 6 h 0.27 1.14 0.32 0.0 0.0 0.0
10628 BRD-K92980438 HCT116 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10879 BRD-K92980438 HEPG2 150 uM 6 h 0.0 0.0 0.0 -0.2 -0.66 0.01
11040 BRD-K92980438 HT29 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11158 BRD-K92980438 MCF??7.00 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11613 BRD-K92980438 NCIH2073 150 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
12170 BRD-K92980438 NCIH596 150 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
12408 BRD-K92980438 NOMO1 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12468 BRD-K92980438 PC3 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12903 BRD-K92980438 SW480 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12983 BRD-K92980438 THP1 150 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
13398 BRD-K92980438 U937 150 uM 6 h -0.27 -1.11 0.38 0.29 1.03 0.5
13706 BRD-K92980438 VCAP 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).